Promethazine is undoubtedly an H1 receptor blocking agent. As well as its antihistaminic action, it provides clinically beneficial sedative and antiemetic effects.???? ????? ????? ?????? ?? ??????? ?? ?? ???? ??? ?? ????? ?? ????? ?? ?? ???? ???? ????? ???? ?? ????? ?? ????? ??? ??? ???? ??? ?????? ?????? ?? ?????? ?? ??? ???? ?? ?? ?? ???? ???????